{"id":5167,"date":"2026-04-24T13:51:47","date_gmt":"2026-04-24T13:51:47","guid":{"rendered":"https:\/\/www.worldpumpnews.com\/?p=5167"},"modified":"2026-04-24T13:51:47","modified_gmt":"2026-04-24T13:51:47","slug":"nasal-spray-slows-brain-ageing","status":"publish","type":"post","link":"https:\/\/www.worldpumpnews.com\/?p=5167","title":{"rendered":"Nasal spray slows brain ageing"},"content":{"rendered":"<p><\/p>\n<div><!--$--><\/p>\n<p><h2>The effects last months<\/h2>\n<\/p>\n<p><!--\/$--><!--$--><\/p>\n<div class=\"custom-prose drop-cap \">\n<p>A new study has revealed that there is a new nasal spray which an reduce brain inflammation and restore memory dramatically.<\/p>\n<\/div>\n<p><!--\/$--><!--$--><\/p>\n<div class=\"custom-prose  \">\n<p>And this can happen in just two doses with effects lasting months, thanks to the new spray developed by scientists.<\/p>\n<\/div>\n<p><!--\/$--><!--$--><!--\/$--><!--$--><\/p>\n<div class=\"custom-prose  \">\n<p>The brain fog one experiences as they grow older is linked to a tide of inflammation deep within the brain\u2019s memory centre, a growing body of research suggests.<\/p>\n<\/div>\n<p><!--\/$--><!--$?--><template id=\"B:0\"\/><!--\/$--><!--$--><\/p>\n<div class=\"custom-prose  \">\n<p>By scientists, this is called \u201cneuroinflammaging\u201d, which is thought to be the inevitable price of growing older.<\/p>\n<\/div>\n<p><!--\/$--><!--$--><\/p>\n<div class=\"custom-prose  \">\n<p>A recent mice study now suggests that a simple nasal spray can actually reverse that this inflammation which causes brain ageing and brain fog.<\/p>\n<\/div>\n<p><!--\/$--><!--$--><\/p>\n<div class=\"custom-prose  \">\n<p>As per researchers from Texas A&amp;M University, the nasal spray in question could change what is known about brain ageing.<\/p>\n<\/div>\n<p><!--\/$--><!--$--><\/p>\n<div class=\"custom-prose  \">\n<p>And it may even reshape the future of therapies for conditions like Alzheimer\u2019s disease.<\/p>\n<\/div>\n<p><!--\/$--><!--$?--><template id=\"B:1\"\/><!--\/$--><!--$?--><template id=\"B:2\"\/><!--\/$--><!--$--><\/p>\n<div class=\"custom-prose  \">\n<p>Ashok Shetty, lead author of the study published in the Journal of Extracellular Vesicles, said: \u201cAs we develop and scale this therapy, a simple, two-dose nasal spray could one day replace invasive, risky procedures or maybe even months of medication\u201d.<\/p>\n<\/div>\n<p><!--\/$--><!--$--><\/p>\n<div class=\"custom-prose  \">\n<p>\u201cOur approach redefines what it means to grow old,\u201d Dr Shetty says.<\/p>\n<\/div>\n<p><!--\/$--><!--$--><\/p>\n<div class=\"custom-prose  \">\n<p>\u201cWe\u2019re aiming for successful brain ageing: keeping people engaged, alert, and connected. Not just living longer, but living smarter and healthier,\u201d he adds.<\/p>\n<\/div>\n<p><!--\/$--><!--$--><\/p>\n<div class=\"custom-prose  \">\n<p>Researchers say that the nasal spray works equally effectively across genders, and may one day even help stroke survivors rebuild lost brain function.<\/p>\n<\/div>\n<p><!--\/$--><!--$--><\/p>\n<div class=\"custom-prose  \">\n<p>It contains millions of microscopic biological parcels known as extracellular vesicles (EVs).<\/p>\n<\/div>\n<p><!--\/$--><!--$?--><template id=\"B:3\"\/><!--\/$--><!--$--><\/p>\n<div class=\"custom-prose  \">\n<p>These act like delivery vehicles to carry powerful genetic cargo called microRNAs, which are the active ingredients.<\/p>\n<\/div>\n<p><!--\/$--><!--$--><\/p>\n<div class=\"custom-prose  \">\n<p>\u201cMicroRNAs act like master regulators. They help modulate and regulate many gene and signalling pathways in the brain,\u201d explained study co-author Madhu Leelavathi Narayana.<\/p>\n<\/div>\n<p><!--\/$--><!--$--><\/p>\n<div class=\"custom-prose  \">\n<p>The MicroRNAs bypass the brain\u2019s protective shield and travel directly into brain tissue, where they are absorbed, with the help of the EVs.<\/p>\n<\/div>\n<p><!--\/$--><!--$--><\/p>\n<div class=\"custom-prose  \">\n<p>Another author of the study, Maheedhar Kodali, said that \u201cthe mode of delivery is one of the most exciting aspects of our approach. Intranasal delivery allows us to reach and treat the brain directly without invasive procedures\u201d.<\/p>\n<\/div>\n<p><!--\/$--><!--$--><\/p>\n<div class=\"custom-prose  \">\n<p>The microRNAs suppress protein systems like NLRP3 and cGAS\u2013STING, which are known to drive chronic inflammation in ageing brains, once in the brain.<\/p>\n<\/div>\n<p><!--\/$--><!--$?--><template id=\"B:4\"\/><!--\/$--><!--$--><\/p>\n<div class=\"custom-prose  \">\n<p>According to scientists, the treatment also recharges the cell power plants, mitochondria, inside the brain\u2019s neurons.<\/p>\n<\/div>\n<p><!--\/$--><!--$--><\/p>\n<div class=\"custom-prose  \">\n<p>In the mice treated with the nasal spray, remarkable improvement was shown not only in recognising familiar objects, but also detecting new objects and changes in their environment.<\/p>\n<\/div>\n<p><!--\/$--><!--$--><\/p>\n<div class=\"custom-prose  \">\n<p>As per the researchers, a US patent has already been filed for the nasal spray.<\/p>\n<\/div>\n<p><!--\/$--><!--$--><\/p>\n<div class=\"custom-prose  \">\n<p>The researchers have said that they hope it could become a breakthrough for brain ageing treatments.<\/p>\n<\/div>\n<p><!--\/$--><\/div>\n<p>#Nasal #spray #slows #brain #ageing<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The effects last months A new study has revealed that there is a new nasal spray which an reduce brain inflammation and restore memory dramatically. And this can happen in just two doses with effects lasting months, thanks to the new spray developed by scientists. The brain fog one experiences as they grow older is [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":5168,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[5354,3661,853,5351,5350,5353,5352],"class_list":{"0":"post-5167","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-featured","8":"tag-ageing","9":"tag-brain","10":"tag-health","11":"tag-nasal","12":"tag-nasal-spray","13":"tag-slows","14":"tag-spray"},"_links":{"self":[{"href":"https:\/\/www.worldpumpnews.com\/index.php?rest_route=\/wp\/v2\/posts\/5167","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.worldpumpnews.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.worldpumpnews.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.worldpumpnews.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.worldpumpnews.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=5167"}],"version-history":[{"count":0,"href":"https:\/\/www.worldpumpnews.com\/index.php?rest_route=\/wp\/v2\/posts\/5167\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.worldpumpnews.com\/index.php?rest_route=\/wp\/v2\/media\/5168"}],"wp:attachment":[{"href":"https:\/\/www.worldpumpnews.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=5167"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.worldpumpnews.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=5167"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.worldpumpnews.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=5167"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}